Yong Wang
共找到 6 条论著文献

1、Pilot study of large-scale production of mutant pigs by ENU mutagenesi

2、Highly uniform Ru nanoparticles over N-doped carbon: pH and temperature-universal hydrogen release from water reduction1 2018

摘要:1 online resource Abstract : Highly uniform ruthenium (Ru) nanoparticles over N-doped carbon (Ru@CN) was designed and confirmed as a promising candidate for the hydrogen evolution reaction (HER) over a wide pH range. Abstract : Highly uniform ruthenium (Ru) nanoparticles over N-doped carbon (Ru@CN) was designed and confirmed as a promising candidate for the hydrogen evolution reaction (HER) over a wide pH range. In particular, outstanding catalytic activity with an overpotential of 32 mV at 10 mA cm −2 was achieved in basic media. Moreover, Ru@CN holds promise for hydrogen production from 0 °C to 60 °C, greatly broadening its applicability.
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3、ESSE 2017 : Proceedings of the International Conference on Environmental Science and Sustainable Energy Ed.by ZhaoYang Dong 2018

摘要:從書:De Gruyter Proceedings 1 online resource (923 p.)
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4、Evaluation of nigrostriatal damage and its change over weeks in a rat model of Parkinson's disease: small animal positron emission tomography studies with [11C]β-CFT

摘要:Introduction: The cardinal pathological feature of Parkinson's disease (PD) is progressive loss of dopaminergic neurons. Since dopamine transporter (DAT) is a protein located presynaptically on dopaminergic nerve terminals, radioligands that bind to these sites are promising radiopharmaceuticals for evaluation of the integrity of the dopamine system. This study using positron emission tomography (PET) tracers, [11C]-2β-carbomethoxy-3β-(4-fluorophenyl)-tropane ([11C]β-CFT, radioligand for DAT), was aimed at evaluating the degree of nigrostriatal damage and its change over weeks in a rat model of PD.Methods: The brains of these rats were unilaterally lesioned by mechanical transection of the nigrostriatal dopamine pathway at the medial forebrain bundle (MFB). Behavioral studies were carried out by apomorphine (APO) challenge prior to and 1, 2 and 4 weeks after MFB axotomy. Small animal PET scans were performed 2 days after the behavioral test. Immunohistochemistry was conducted 4 days after the last PET scan.Results: Compared with the contralateral intact side, a progressively decreased [11C]β-CFT binding was observed on the lesioned side which correlated inversely with the APO-induced rotations. Postmortem immunohistochemical studies confirmed the loss of both striatal dopamine fibers and nigral neurons on the lesioned side.Conclusion: These findings not only demonstrate that the neuronal degeneration in this model is relatively slow, but also suggest [11C]β-CFT is a sensitive marker to monitor the degree of nigrostriatal damage and its change over weeks. This marker can be used prospectively to study the progression of the disease, thereby making detection of early phases of PD possible.
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5、Poster Abstract

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6、The Role of Amino Acid Esters and the Amide Group in the Chiral Induction Process by a Novel Monoamide-Linked Monozinc Bisporphyrinate Role of Amino Acid Esters in Chiral Induction by Monozinc Bisporphyrinate