Lin Zhang
共找到 23 条论著文献

1、Chinese lion dance = Zhongguo wu shi

摘要:從書:Chinese art (Huwa Golden International (Firm)) 1 videodisc (30 min.) : sound, color ; 4 3/4 in. Provides information about the history, significance and contemporary performance of the Chinese lion dance.
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2、Operation performance and simulation of internally heat-integrated distillation column

3、Novel D-π-A-π-D structural 2, 2′-bipyridine derivatives with different electron donors: Structure, one- and two-photon excited fluorescence and bioimaging

4、Development and Validation of a Prognostic Nomogram in AFP-negative hepatocellular carcinoma

5、Dapagliflozin treatment for type 2 diabetes: a systematic review and meta-analysis of randomized controlled trial

摘要:Context: Type 2 diabetes has reached epidemic proportions and places a heavy burden on society. Dapagliflozin is a novel treatment choice for type 2 diabetes.Objective: A meta-analysis of randomized controlled trials (RCTs) was conducted to assess the efficacy and safety of dapagliflozin treatment.Data Sources: Medline (via PubMed), Embase (via OVID) and the Cochrane Library (up to August 2012) were searched, and RCTs were collected.Study Selection: Studies included type 2 diabetic subjects, who had been treated with dapagliflozin, and recorded HbA1c as outcomes.Data Extraction: Two reviewers independently assessed articles and study quality. Patient characteristics, interventions and outcomes were collected.Data Synthesis: Ten RCTs were included. Risk of bias for outcomes was low. Fixed or random effects models were used to pool the results. Dapagliflozin treatment was associated with a reduction in HbA1c [weighted mean difference (WMD): -0.53%; 95% confidence interval (CI): −0.58% to −0.47%; p p p p = 0.17], although hypoglycaemic risk increased (RR: 1.16; 95% CI: 1.05, 1.29; p = 0.005) when dapagliflozin was combined with other hypoglycaemic drugs. Dapagliflozin increased urinary glucose excretion (WMD: 26.98; 95% CI: 21.72, 32.24; p p = 0.004) and genital tract infections (RR: 3.23; 95% CI: 2.50, 4.18; p = 0.00001).Conclusions: Dapagliflozin appears to be an effective treatment for type 2 diabetes, although it may increase the risk of urinary tract infections and genital tract infections. Copyright © 2013 John Wiley & Sons, Ltd.
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6、AsiaSim 2012 : Asia Simulation Conference 2012, Shanghai, China, October 27-30, 2012, Proceedings. Part II 2012

摘要:從書:Communications in computer and information science, 324. 1 online resource. The Three-Volume-Set CCIS 323, 324, 325 (AsiaSim 2012) together with the Two-Volume-Set CCIS 326, 327 (ICSC 2012) constitutes the refereed proceedings of the Asia Simulation Conference, AsiaSim 2012, and the International Conference on System Simulation, ICSC 2012, held in Shanghai, China, in October 2012.  再讀一些...
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7、AsiaSim 2012 : Asia Simulation Conference 2012, Shanghai, China, October 27-30, 2012, Proceedings. Part I 2012

摘要:從書:Communications in computer and information science, 323. 1 online resource. The Three-Volume-Set CCIS 323, 324, 325 (AsiaSim 2012) together with the Two-Volume-Set CCIS 326, 327 (ICSC 2012) constitutes the refereed proceedings of the Asia Simulation Conference, AsiaSim 2012, and the International Conference on System Simulation, ICSC 2012, held in Shanghai, China, in October 2012.  再讀一些...
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8、Tetramethylpyrazine can ameliorate hepatocellular mitochondrial dysfunction by decreasing the inflammatory response and increasing AQP8 protein expression in septic rat

摘要:1 online resource Sepsis, which could lead to mitochondrial dysfunction and cellular energy loss, always induces acute liver injury and has a high mortality rate. Tetramethylpyrazine (TMP) is an active extract from the Chinese herb Ligusticum chuanxiong and exhibits anti-sepsis activity. In this study, a rat sepsis model was first established via cecal ligation and puncture (CLP). Then, 48 Sprague Dawley male rats were randomly divided into four groups (12 rats in each group): control group (C), sepsis group (S), TMP treatment group (T), and TMP prevention group (P). Serum aspartate aminotransferase (AST), serum alanine aminotransferase (ALT), mitochondrial aspartate aminotransferase (mAST), and adenosine triphosphate (ATP) levels and mitochondrial membrane potential (MMP) were measured and used as indicators of hepatic dysfunction severity and mitochondrial function. In addition, the activities of Na-K-ATPase, Mg-ATPase, Ca-ATPase, and Ca-Mg-ATPase in the mitochondrial membrane, the expression level of AQP8 and some inflammatory factors, and the level of oxidative stress were measured to explore potential mechanisms. We found that AQP8 accepts signals from inflammatory factors upon stimulation and during various infections, and low AQP8 expression levels could result in further downstream mitochondrial dysfunction. In conclusion, our data demonstrated that TMP could ameliorate hepatocellular mitochondrial dysfunction by decreasing the inflammatory response and increasing AQP8 protein expression.
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9、Dapagliflozin treatment for type 2 diabetes: a systematic review and meta-analysis of randomized controlled trials Dapagliflozin Treatment for Type 2 Diabetes: Meta-analysi

10、A Randomized Clinical Trial of High-Dosage Coenzyme Q10 in Early Parkinson Disease No Evidence of Benefit

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11、Peroxisome proliferator activated receptor gamma in human placenta may mediate the adverse effects of phthalates exposure in pregnancy

摘要:• Placental peroxisome proliferator activated receptors gamma expression is up-regulated by phthalates exposure. • Placental peroxisome proliferator activated receptors gamma expressionis associated with preterm delivery. • Estrogens and matrix metalloproteinases in cord blood is negatively associated with phthalates exposure. • Estrogens and matrix metalloproteinases is down-regulated by placental peroxisome proliferator activated receptors gamma.Peroxisome-proliferator activated receptor gamma (PPARG) in placenta play an important role in pregnancy. Our previous study showed that it mediated the effects of phthalates on placental mRNA expression of estrogen synthetases in rats. To assess the effects of phthalate exposure on PPARG placental expression, and the contribution of PPARG to the effects of phthalates in human. 207 healthy pregnant women were recruited and their cord blood and placenta were collected upon delivery. Three phthalates, estrogens in cord blood and protein expression of PPARG in placenta were measured. Linear regression were used to analyze the relationship between phthalates exposure, PPARG expression and hormones. Phthalate levels in cord blood were positively associated with PPARG protein expression in placenta (p
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12、Clustering Personalized 3D Printing Models with Multiple Modal CNN

13、System simulation and scientific computing : International Conference, ICSC 2012, Shanghai, China, October 27-30, 2012. Proceedings. Part II 2012

摘要:從書:Communications in computer and information science, 327. 1 online resource. The Three-Volume-Set CCIS 323, 324, 325 (AsiaSim 2012) together with the Two-Volume-Set CCIS 326, 327 (ICSC 2012) constitutes the refereed proceedings of the Asia Simulation Conference, AsiaSim 2012, and the International Conference on System Simulation, ICSC 2012, held in Shanghai, China, in October 2012.  再讀一些...
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14、Investigation on heat transfer and optimization of internally heat-integrated distillation column

15、Mycobacterium chelonae sensitisation induces CD4+-mediated cytotoxicity against BCG

16、DNA Cleavage is Independent of Synapsis during Streptomyces Phage φBT1 Integrase-Mediated Site-Specific Recombination

17、A novel role for thyroid-stimulating hormone: Up-regulation of hepatic 3-hydroxy-3-methyl-glutaryl-coenzyme a reductase expression through the cyclic adenosine monophosphate/protein kinase A/cyclic adenosine monophosphate-responsive element binding protei

摘要:Elevated thyroid-stimulating hormone (TSH) and hypercholesterolemia commonly coexist, as typically seen in hypothyroidism, but there is no known mechanism directly linking the two. Here, we demonstrated that in liver cells, TSH promoted the expression of 3-hydroxy-3-methyl-glutaryl coenzyme A reductase (HMGCR), a rate-limiting enzyme in cholesterol synthesis, by acting on the TSH receptor in hepatocyte membranes and stimulating the cyclic adenosine monophosphate / protein kinase A / cyclic adenosine monophosphate-responsive element binding protein (cAMP/PKA/CREB) signaling system. In thyroidectomized rats, the production of endogenous thyroid hormone was eliminated and endogenous TSH was suppressed through pituitary suppression with constant administration of exogenous thyroid hormone, and hepatic HMGCR expression was increased by administration of exogenous TSH. These results suggested that TSH could up-regulate hepatic HMGCR expression, which indicated a potential mechanism for hypercholesterolemia involving direct action of TSH on the liver. (HEPATOLOGY 2010)
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18、AsiaSim 2012 : Asia Simulation Conference 2012, Shanghai, China, October 27-30, 2012, Proceedings. Part III 2012

摘要:從書:Communications in computer and information science, 325. 1 online resource. The Three-Volume-Set CCIS 323, 324, 325 (AsiaSim 2012) together with the Two-Volume-Set CCIS 326, 327 (ICSC 2012) constitutes the refereed proceedings of the Asia Simulation Conference, AsiaSim 2012, and the International Conference on System Simulation, ICSC 2012, held in Shanghai, China, in October 2012.  再讀一些...
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19、Identification of 7 New S-Alleles and S-Genotypes Assignments in Chinese Pear

20、System simulation and scientific computing : International conference, ICSC 2012, Shanghai, China, October 27-30, 2012, Proceedings. Part I 2012

摘要:從書:Communications in computer and information science, 326. 1 online resource. The Three-Volume-Set CCIS 323, 324, 325 (AsiaSim 2012) together with the Two-Volume-Set CCIS 326, 327 (ICSC 2012) constitutes the refereed proceedings of the Asia Simulation Conference, AsiaSim 2012, and the International Conference on System Simulation, ICSC 2012, held in Shanghai, China, in October 2012.  再讀一些...
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