Makoto Takahashi
共找到 16 条论著文献

1、Influences of trunk flexion on mechanical energy flow in the lower extremities during gait

2、Sponge Ni catalyst with high activity in CO2 methanation

摘要:CO2 methanation over sponge Ni was investigated. When CO2 methanation was carried out using sponge Ni without any pretreatment, the sponge Ni exhibited a CO2 conversion of 83% at 250 °C under a high space velocity (0.11 molCO2 gcat
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3、Surgical Results and Related Factors for Ossification of Posterior Longitudinal Ligament of the Thoracic Spine A Multi-Institutional Retrospective Study

4、Graphic analysis of microscopic tumor cell infiltration, proliferative potential, and vascular endothelial growth factor expression in an autopsy brain with glioblastoma

摘要:BACKGROUND Growth of brain tumors requires tumor-cell attachment to adjacent structures, degradation of surrounding matrixes, migration of tumor cells, proliferation of vasculature, and tumor cell proliferation. Comparison of the findings on neuroimaging, degrees and patterns of tumor invasion, regional tumor cell viability detected by Ki-67 immunohistochemistry, and regional vascular endothelial growth factor (VEGF) expression in whole-brain specimen of glioblastoma therefore is of great interest, and will facilitate study of the host reaction against the glioblastoma. METHODS We graphically analyzed microscopic tumor-cell infiltration, regional differences in Ki-67 labeling indices (LI), and immunohistochemical expression of VEGF in an autopsy brain with glioblastoma. RESULTS Glioblastoma cells infiltrated the brain far beyond the gross limits of the tumor and the areas with high signal intensity on T2-weighted magnetic resonance images. A wide range of histologic malignancy was apparent from hematoxylin-eosin staining and the Ki-67 labeling indices. VEGF was highly expressed in normal astrocytes located outside the tumor. CONCLUSION Graphic analysis of histologic and immunohistochemical patterns is a useful method of investigating the mechanisms of glioma growth, tumor cell infiltration in the brain, and the host reaction of the brain against neoplasms.
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5、Electric and thermoelectric properties of electrodeposited bismuth telluride (Bi2Te3) film

6、A study of survival in patients with stomach cancer treated by a combination of preoperative intra-arterial infusion therapy and surgery

7、Excitability changes in human hand motor area induced by voluntary teeth clenching are dependent on muscle propertie

摘要:To investigate whether the early effects of voluntary teeth clenching (VTC) among the first dorsal interosseous (FDI), abductor digiti minimi (ADM), and abductor pollicis brevis (APB) muscles are differently modulated depending on their muscle properties, we examined the responses of motor evoked potentials (MEPs) elicited by transcranial magnetic stimulation with selected current directions and by brainstem magnetic stimulation (BMS). Although MEP responses with anterior-medially current direction (preferentially elicited I1-waves) were facilitated in all three muscles, those responses with posterior-laterally current direction (preferentially elicited I3-waves) were different among FDI, ADM, and APB muscles. That is, MEP responses in FDI and APB muscles were significantly reduced, whereas those responses in ADM muscle were not significantly reduced. Further, inhibitory effects of VTC in FDI muscle were more potent than those in ADM or APB muscles. On the other hand, the responses to BMS were unchanged by VTC in all three muscles, suggesting that the modulations of MEP were attributed to the cortical origin. On the basis of our previous findings that the inhibitory connections in FDI muscle are more potent than those in ADM muscle (Takahashi et al. in Clin Neurophysiol 116:2757-2764, 2005), the cortical effects of VTC among three hand muscles are differently modulated, depending on muscle properties, presumably the extents of inhibitory connections to corticospinal tract neurons. Considering that the functional capacity in FDI muscle is higher than that in ADM or APB muscles, the cortical inhibitory effect of VTC might contribute to the sophisticated regulation of the motor outputs even during VTC.
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8、Ag addition to CuO-ZrO2 catalysts promotes methanol synthesis via CO2 hydrogenation

摘要:The effect of adding Ag to CuO-ZrO2 catalysts for the hydrogenation of CO2 to methanol was investigated using CuO-ZrO2, Ag/CuO-ZrO2, and Ag/ZrO2. The addition of Ag to CuO-ZrO2 catalysts decreased the specific surface area and also broke its mesostructure. Thus, Ag played a significant role as a sintering aid in the preparation of Ag/CuO-ZrO2 catalysts. We note that the as-prepared Ag/CuO-ZrO2 catalysts contained Ag + and Zr
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9、Diagnostic classification of schizophrenia by neural network analysis of blood-based gene expression signature

摘要:Gene expression profiling with microarray technology suggests that peripheral blood cells might be a surrogate for postmortem brain tissue in studies of schizophrenia. The development of an accessible peripheral biomarker would substantially help in the diagnosis of this disease. We used a bioinformatics approach to examine whether the gene expression signature in whole blood contains enough information to make a specific diagnosis of schizophrenia. Unpaired t-tests of gene expression datasets from 52 antipsychotics-free schizophrenia patients and 49 normal controls identified 792 differentially expressed probes. Functional profiling with DAVID revealed that eleven of these genes were previously reported to be associated with schizophrenia, and 73 of them were expressed in the brain tissue. We analyzed the datasets with one of the supervised classifiers, artificial neural networks (ANNs). The samples were subdivided into training and testing sets. Quality filtering and stepwise forward selection identified 14 probes as predictors of the diagnosis. ANNs were then trained with the selected probes as the input and the training set for known diagnosis as the output. The constructed model achieved 91.2% diagnostic accuracy in the training set and 87.9% accuracy in the hold-out testing set. On the other hand, hierarchical clustering, a standard but unsupervised classifier, failed to separate patients and controls. These results suggest analysis of a blood-based gene expression signature with the supervised classifier, ANNs, might be a diagnostic tool for schizophrenia.
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10、Durability of Ni/TiO2 catalyst containing trace chlorine for CO selective methanation

11、Magnetic Resonance Imaging Findings in Cerebral Fat Embolism: Correlation with Clinical Manifestation

12、In vitro sensitivity test of stomach cancer tissues by the use of metal grid method

13、33. Factors Influencing the Results of Surgery for Ossification of the Posterior Longitudinal Ligament in the Thoracic Spine—A Multi-institutional Retrospective Study

14、Central command increases muscular oxygenation of the non‐exercising arm at the early period of voluntary one‐armed cranking 2017

15、Differential contribution of ACh-muscarinic and β-adrenergic receptors to vasodilatation in noncontracting muscle during voluntary one-legged exercise 2014

16、Combined laparoscopic abdominoperineal resection and robotic‐assisted prostatectomy for synchronous double cancer of the rectum and the prostate 2016

摘要:1 online resource Abstract: Here we report a combined laparoscopic abdominoperineal resection and robotic‐assisted prostatectomy. A 74‐year‐old man was diagnosed with T4b low rectal and prostate cancer. The operation was performed after neoadjuvant chemotherapy for the rectal cancer. The procedure used eight ports in total, five for laparoscopic abdominoperineal resection and six for robotic‐assisted prostatectomy. First, laparoscopic total mesorectal excision including division of the inferior mesenteric artery was performed, and then, robotic dissection of the prostate was performed. The en bloc specimen was removed through the perineal wound. Then, robotic urethrovesical anastomosis was performed. An extraperitoneal end colostomy was created to finish the operation. The operating time was 545 min, and blood loss was 170 mL. The postoperative course was uneventful, and the patient discharged on postoperative day 17. The combined laparoscopic abdominoperineal resection and robotic‐assisted prostatectomy were performed safely without any additional technical difficulty, as both procedures shared port settings and patient positions.
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