Limin Zhang
共找到 11 条论著文献

1、4-Regular Graphs without 3-Regular Subgraph

2、Enhancing Akt Imaging through Targeted Reporter Expression

3、The domain structure and mobility of semi-crystalline poly(3-hydroxybutyrate) and poly(3-hydroxybutyrate-co-3-hydroxyvalerate): A solid-state NMR study

摘要:Solid-state NMR techniques have been employed to investigate the domain structure and mobility of the bacterial biopolymeric metabolites such as poly(3-hydroxybutyrate) (PHB) and its copolymers poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) containing 2.7 mol% (PHBV2.7) and 6.5 mol% (PHBV6.5) 3-hydroxyvalerate. Both single-pulse excitation with magic-angle spinning (SPEMAS) and cross-polarization magic-angle spinning (CPMAS) 13C NMR results showed that these biopolymers were composed of amorphous and crystalline regions having distinct molecular dynamics. Under magic-angle spinning, 1H T 1ρ and 13C T 1 showed two processes for each carbon. Proton relaxation-induced spectral editing (PRISE) techniques allowed the neat separation of the 13C resonances in the crystalline regions from those in the amorphous ones. The proton spin-lattice relaxation time in the tilted rotating frame, H T 1 ρ T , measured using the Lee-Goldburg sequence with frequency modulation (LGFM) as the spin-locking scheme, was also double exponential and significantly longer than 1H T 1ρ . The difference between H T 1 ρ T for the amorphous and crystalline domains was greater than that of 1H T 1ρ . Our results showed that the H T 1 ρ T differences could be exploited in LGFM-CPMAS experiments to separate the signals from two distinct regions. 1H spin-diffusion results showed that the domain size of the mobile components in PHB, PHBV2.7 and PHBV6.5 were about 13, 24 and 36 nm whereas the ordered domain sizes were smaller than 76, 65 and 55 nm, respectively. The results indicated that the introduction of 3-hydroxyvalerate into PHB led to marked molecular mobility enhancement in the biopolymers.
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4、Limiting Tolerable Settlement and Angular Distortion for Building Foundation

摘要:To develop reliability-based serviceability criteria for foundation design, the probability distributions of limiting tolerable displacements should be available. In this study, displacement information of 380 buildings, including .124 cases from Hong Kong and Mainland China, is collected for analysis. The background information of these buildings is described. The buildings are divided into four categories for study: soil type, foundation type, structural type, and building usage. Based on the observed performance of these buildings, distributions of the limiting tolerable settlement and angular distortion for each building category are established following a probability-based procedure. The statistics of the limiting tolerable settlement and angular distortion are obtained. It is found that the limiting tolerable displacements of structures of different categories differ significantly. The tolerable displacement distributions can be used directly for full probability-based design or for determining allowable displacements for limit-state or conventional design.
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5、Dam failure mechanisms and risk assessment 2016

摘要:1 ressource en ligne (xx, 476 pages) : illustration
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6、Developing Partial Factors for Serviceability Limit State Design of Large-Diameter Bored Pile

摘要:The serviceability requirement in terms of total settlement can be expressed in terms of predicted settlement and limiting tolerable settlement with necessary modifications for group effects and system effects. Similar to the LRFD methodology for ultimate limit design, partial factors can be applied to both limiting tolerable settlement and predicted settlement to attain a specified level of safety. In this paper, partial factors for serviceability design of large-diameter bored piles are developed using a first order reliability method, based on the statistics of prediction model performance, as well as the statistics of limiting tolerable settlement obtained previously. Five combinations of analysis methods for large-diameter bored piles in soils and six combinations of analysis methods for large-diameter bored piles socketed in rocks are considered.
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7、The aryl hydrocarbon receptor as a moderator of host-microbiota communication

摘要:The aryl hydrocarbon receptor (AHR) is an important component of the host-microbiota communication network. Comparisons of wild-type and Ahr-null mice as well as from exposure studies with potent AHR ligands (e.g., 2,3,7,8-tetrachlorodibenzo-p-dioxin) have provided compelling evidence that the AHR may be a master regulator of the host-microbiota interaction thus helping to shape the immune system and impact host metabolism. Metabolomics and sequenced-based microbial community profiling, two recent technological advances, have helped to solidify this host-microbiota signaling concept and identified not only how specific ligands generated by the host and by the microbiota can activate the AHR, but also how activation/disruption of the AHR can influence and shape the microbiota. We are just beginning to understand how the temporal nature and tissue- and microbiota-specific generation of AHR ligands contribute to many AHR-dependent processes. In this review, we focus on several recent advances where metabolomics and characterization of the microbiota structure and function have generated new perspectives by which to evaluate AHR activity.• Metabolomic approaches have clarified the metabolic consequences of AHR activation. • AHR genotype and activation by diverse ligands impacts the microbiota. • Timing, dose, exposure route, and type of AHR ligand are areas to further explore.
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8、Dam Failure Mechanisms and Risk Assessment 2016

9、Combined therapy using LHRH-PE40 and anti-CD40 dendritic cells substantially eliminate tumor cells ZHANG

10、EGFR‐targeted therapy alters the tumor microenvironment in EGFR‐driven lung tumors: implications for combination therapie

11、Unraveling the concentration-dependent metabolic response of Pseudomonas sp. HF-1 to nicotine stress by 1H NMR-based metabolomic